Declarative memory in older people with dementia, mild cognitive impairment, and controls
PDF (Español)

Keywords

Aging
Memory
Older adult
Cognitive functioning
Amnesia Envejecimiento
Memoria
Adulto mayor
Funcionamiento cognitivo
Amnesia

Abstract

Background. There is strong evidence that people with dementia show poor performance in declarative memory, relative to older healthy people. However, studies on possible differences in declarative (verbal) memory performance between patients with amnesic-type MCI and healthy patients are scarce, and the data are not conclusive. Objective. To determine the performance in declarative memory of three groups of older people; a) with probable dementia (n=63), b) MCI (n=20), and c) "healthy" (n=30). Method. The Montreal Cognitive Assessment and an instrument based on the Rey Auditory Verbal Learning Test were applied. Results. Differences in memory scores were observed between participants with dementia and those with MCI and "healthy", but not between these last two groups. Significant moderate and positive correlations were found between MoCA and remembered words. Discussion. Although the deficit in declarative memory occurs in the group with probable dementia as well as in the other two, it was not observed between the MCI group and the "healthy" controls. The results show that, in general, the participants with MCI do not show deficits in declarative memory, which can be attributed to the heterogeneity of the MCI. Therefore, the need arises to continue exploring the performance of declarative memory, differentiating by MCI subtyp.

https://doi.org/10.25009/pys.v32i2.2740
PDF (Español)

References

Alanís N., G., Garza M., J.V. y González A., A. (2008). Prevalencia de demencia en pacientes geriátricos. Revista Médica del Instituto Mexicano del Seguro Social, 46(1), 27-32.

Almkvist, O., Bosnes, O., Bosnes, I. y Stordal, E. (2019). Subjective working and declarative memory in dementia and normal aging. Acta Neurologica Scandinavica, 140(2), 140-146. Doi: 10.1111/ane.13114.

American Psychiatric Association (2000). Diagnostic and statistical manual of mental disorders (4th ed.). Washington, DC: APA. Doi: 10.1017/s0033291700035765.

American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders (5th ed.). Washington, DC: APA. Doi: 10.1108/rr-10-2013-0256.

Cambridge, O.R., Knight, M.J., Mills, N. y Baune, B.T. (2018). The clinical relationship between cognitive impairment and psychosocial functioning in major depressive disorder: a systematic review. Psychiatry Research, 269, 157-171. Doi: 10.1016/j.psychres.2018.08.033.

Ceci, S.J. (1991). How much does schooling influence general intelligence and its cognitive components? A reassessment of the evidence. Developmental Psychology, 27(5), 703. Doi: 10.1037/0012-1649.27.5.703.

Costa, A., Perri, R., Serra, L., Barban, F., Gatto, I., Zabberoni, S. y Carlesimo, G.A. (2010). Prospective memory functioning in mild cognitive impairment. Neuropsychology, 24(3), 327-335. Doi: 10.1037/a0018015.

Custodio, N., Herrera, E., Lira, D., Montesinos, R., Linares, J. y Bendezú, L. (2012). Deterioro cognitivo leve: ¿dónde termina el envejecimiento normal y empieza la demencia? Anales de la Facultad de Medicina, 73(4) 321-330.

Dubois, B., Feldman, H.H., Jacova, C., DeKosky, S.T., Barberger-Gateau, P., Cummings, J. y Meguro, K. (2007). Research criteria for the diagnosis of Alzheimer’s disease: revising the NINCDS–ADRDA criteria. The Lancet Neurology, 6(8), 734-746. Doi: 10.1016/S1474-4422(07)70178-3.

Einstein, G.O. y McDaniel, M.A. (1990). Normal aging and prospective memory. Journal of Experimental Psychology: Learning, Memory, and Cognition, 16, 717-726. Doi: 10.1037/0278-7393.16.4.717.

Fleming, R., Zeisel, J. y Bennett, B. (2020) World Alzheimer Report 2020. Design, Dignity, Dementia: Dementia-related design and the built environment (v. I. September. London: Alzheimer’s Disease International.

Ginsberg, T.B., Powell, L., Patel, A., Emrani, S., Chopra, A., Cavalieri, T. y Libon, D. J. (2017). Frailty phenotype and neuropsychological test performance: a preliminary analysis. The Journal of the American Osteopathic Association, 117(11), 683-687.

Gurven, M., Fuerstenberg, E., Trumble, B., Stieglitz, J., Beheim, B., Davis, H. y Kaplan, H. (2017). Cognitive performance across the life course of Bolivian forager-farmers with limited schooling. Developmental Psychology, 53(1), 160-176. Doi: 10.1037/dev0000175.

Gutiérrez, J.P., Rivera D., J., Shamah L., T., Villalpando H., S., Franco, A., Cuevas N., L., Romero M., M. y Hernández Á., M. (2012). Encuesta Nacional de Salud y Nutrición 2012. Resultados Nacionales. Cuernavaca (México): Instituto Nacional de Salud Pública.

Harmer, C.J. y Cowen, P.J. (2013). It’s the way that you look at it’s a cognitive neuropsychological account of SSRI action in depression. Philosophical Transactions of the Royal Society B: Biological Sciences, 368(1615), 20120407. Doi: 10.1098/rstb.2012.0407.

Janicki M., P., Watchman, K. y Fortea O., J. (2018). Principales conclusiones acordadas durante la Cumbre sobre Discapacidad Intelectual y Demencia. Siglo Cero, 49(2), 115-122. Recuperado de https://www.storre.stir.ac.uk/bitstream/1893/ 27371/1/18615-63186-2-P.pdf.

Jirsaraie, R.J., Sheffield, J.M. y Barch, D.M. (2018). Neural correlates of global and specific cognitive deficits in schizophrenia. Schizophrenia Research, 201, 237-242. Doi: 10.1016/j.schres.2018.06.017.

Kanaya, A.M., Barrett-Connor, E., Gildengorin, G. y Yaffe, K. (2004). Change in cognitive function by glucose tolerance status in older adults. Archives of Internal Medicine, 29, 494-501. Doi: 10.1001%2Farchinte.164.12.1327.

Libon, D. J., Xie, S. X., Eppig, J., Wicas, G., Lamar, M., Lippa, C. y Wambach, D.M. (2010). The heterogeneity of mild cognitive impairment: A neuropsychological analysis. Journal of the International Neuropsychological Society, 16(1), 84-93. Doi: 10.1017/s1355617709990993.

Lima, I.M., Peckham, A.D. y Johnson, S.L. (2018). Cognitive deficits in bipolar disorders: Implications for emotion. Clinical Psychology Review, 59, 126-136. Doi: 10.1016/j.cpr.2017.11.006.

Llibre G., J.C., Guerra H., M.A. y Perera M., E. (2008). Impacto psicosocial del síndrome demencial en cuidadores cruciales. Revista Cubana de Medicina General Integral, 24(1), 1-15.

Manzini, J.L. (2000). Declaración de Helsinki: principios éticos para la investigación médica sobre sujetos humanos. Acta Bioethica, 6(2), 321-334. Doi: 10.4067/S1726-569X2000000200010.

Mora S., S., García G., R., Perea B., M.V., Ladera F., V., Unzueta A., J., Patiño A., M.C. y Rodríguez S., E. (2012). Deterioro cognitivo leve: detección temprana y nuevas perspectivas. Revista de Neurología, 54(5), 303-310. Doi: 10.33588/rn.5405.2011538.

Nasreddine, Z.S., Phillips, N.A., Bédirian, V., Charbonneau, S., Whitehead, V., Collin, I., Cummings, J.L. y Chertkow, H. (2005). The Montreal Cognitive Assessment, MoCA: a brief screening tool for mild cognitive impairment. Journal of the American Geriatrics Society, 53(4), 695-699. Doi: 10.1111/j.1532-5415.2005.53221.x.

Nestor, P.J., Fryer, T. D. y Hodges, J.R. (2006). Declarative memory impairments in Alzheimer’s disease and semantic dementia. Neuroimage, 30(3), 1010-1020. Doi: 10.1016/j.neuroimage.2005.10.008.

Organización Panamericana de la Salud (2013) Demencia. Una prioridad de la salud pública. Washington: OPS-OMS.

Petersen, R.C. (2011). Mild cognitive impairment. New England Journal of Medicine, 364(23), 2227-2234. Doi: 10.1056/nejmcp0910237.

Poettrich, K., Weiss, P.H., Werner, A., Lux, S., Donix, M., Gerber, J. y Holthoff, V.A. (2009). Altered neural network supporting declarative long-term memory in mild cognitive impairment. Neurobiology of Aging, 30(2), 284-298. Doi: 10.1016/j.neurobiolaging.2007.05.027.

Prince, M., Acosta, D., Ferri, C.P., Guerra, M., Huang, Y., Rodriguez J., J.L. y Acosta, I. (2012). Dementia incidence and mortality in middle-income countries, and associations with indicators of cognitive reserve: a 10/66 Dementia Research Group population-based cohort study. The Lancet, 380(9836), 50-58. Doi: 10.1016/s0140-6736(12)60399-7.

Pringle, A., Browning, M., Cowen, P.J. y Harmer, C.J. (2011). A cognitive neuropsychological model of antidepressant drug action. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 35(7), 1586-1592. Doi: 10.1016/j.pnpbp.2010.07.022.

Rey, A. (1964). L’examen clinique en psychologie (Clinical tests in psychology). Paris: Presses Universitaires de France.

Rodríguez, B., Ramírez, L., Saracco Á., R., Escamilla O., R. y Fresán O., A. (2014). Validez de la Escala de Evaluación Cognitiva de Montreal (MoCA) para determinar deterioro cognitivo en pacientes con esquizofrenia. Salud Mental, 37(6), 517-522. Doi: 10.17711/sm.0185-3325.2014.062.

Saez F., J.A., Lee, L. y Walker, Z. (2007). Long-term outcome of depressive pseudodementia in the elderly. Journal of Affective Disorders, 101(1), 123-129. Doi: 10.1016/j.eurpsy.2007.01.099.

Solís, A. (2018). Utilidad de una evaluación neuropsicológica informatizada de la memoria verbal: el Cogval-Verbal, para la detección del deterioro cognitivo. Datos preliminares. Investigación y Pensamiento Crítico, 6(1), 5-16. Doi: 10.37387/ipc.v6i1.77.

Steffens, D.C. y Potter, G.G. (2008). Geriatric depression and cognitive impairment. Psychological Medicine, 38(2), 163-175. Doi: 10.1017/s003329170700102x.

Thompson, C., Henry, J.D., Rendell, P. G., Withall, A. y Brodaty, H. (2010). Prospective memory function in mild cognitive impairment and early dementia. Journal of the International Neuropsychological Society, 16(2), 318-325. Doi: 10.1017/S1355617709991354.

Triadó, C. (2006). Cambios físicos en el envejecimiento. En F. Villar P. y M. C. Triadó T. (Coords.): Psicología de la Vejez (pp. 65-86). Madrid: Alianza Editorial.

Wimo, A. y Prince, M.J. (2010). World Alzheimer Report 2010: The global economic impact of dementia. Alzheimer's Disease International.

World Health Organization (1992). International Statistical Classification of Diseases and Related Health Problems (10th rev.). Geneva: WHO.

Zurique, C., Cadena, M.O., Zurique, M., Camacho, P.A., Sánchez, M., Hernández, S., Velásquez, K. y Ustate, A. (2019). Prevalencia de demencia en adultos mayores de América Latina: revisión sistemática. Revista Española de Geriatría y Gerontología, 54(6), 346-355. Doi: 10.1016/j.regg.2018.12.007.